Discussion of histidine and zinc finger involvement in PFS

[Helen]

This is a continuation of the discussion on this topic that I created a week ago https://www.hackstasis.com/viewtopic.php?f=2&t=289 where I outlined possible ways to increase zinc finger



I had to take down this thread, since I think it is not a sure thing and a lot of people are going to be jumping around there and potentially hurting themselves. I think it is wrong to post a protocol until we know for sure what is going.

Let have this thread to discuss zinc finger involvement into PSSD< PFS

Histdine cysteine and zinc are the part of the zinc finger. Histidine is a part of the the histamine reaction. We know that PSSD people have anorgasmia and low histamines. the reason I took down this thread, since the more I am looking into this the more I see that it could be high histidine or low histidine.

I would assume high hidistine also could stabilize mast cells. And basically kills all histamine. reactions which is orgasm and excitement

or the second case, could be low histamine and low histidine with low zinc and b6, so low histamines.

I thought we need to figure this out first and then post protocols.


THIS IS NOTHING NEW. IT IS NOT A NEW THEORY. It is still about cortisol and progesterone receptors. That we can affect with Ella, Ru, progesterone and dexamethasone. And the mineral routes that I outlined before

It is just now We are trying to research and adjust cortisol and progesterone reception directly thru the mineral route. That is why I am theorizing on the zinc finger part.

 

[Orion]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="gbolduev" post_id="5824" time="1512415687" user_id="90"><s>

</s>
1) First you have to increase your catalytic triad. Which is HISTIDINE , SERINE, ASPARTIC ACID( limiting in LH rise so should increase your steroids.). these you take in increased quantities( take them with a little HCL, or buy them in HCL form) . These are the center of your digestive system.<br/>
<br/>
then you need to buy amino acids: <br/>
<br/>
lysine, arginine, tyrosine, phenylalanine, alanine, glycine, valine.( these will make your digestive enzymes)
<e>

</e></QUOTE>

Gelatin/Collagen Hydrolysate contain all these aminos, from Histidine to Valine, or do you need large quantities?<br/>
<br/>
How much/dosages?</r>

 

[Helen]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="Orion" post_id="5834" time="1512417361" user_id="56"><s>

</s>
<QUOTE author="gbolduev" post_id="5824" time="1512415687" user_id="90"><s>

</s>
1) First you have to increase your catalytic triad. Which is HISTIDINE , SERINE, ASPARTIC ACID( limiting in LH rise so should increase your steroids.). these you take in increased quantities( take them with a little HCL, or buy them in HCL form) . These are the center of your digestive system.<br/>
<br/>
then you need to buy amino acids: <br/>
<br/>
lysine, arginine, tyrosine, phenylalanine, alanine, glycine, valine.( these will make your digestive enzymes)
<e>

</e></QUOTE>

Gelatin/Collagen Hydrolysate contain all these aminos, from Histidine to Valine, or do you need large quantities?<br/>
<br/>
How much/dosages?
<e>

</e></QUOTE>

gelatin has very little histidine. And also it is full of lead</r>

 

[JonnyCraig]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<t>Thanks gbolduev!<br/>
<br/>
Quick question about the diet portion... good carbs=rice - what kind of rice specifically? I like to only get and eat the best of the best, money not an option. Are we talking simply white rice here, or???<br/>
<br/>
Also, I stopped eating any carbs from wheat and whatnot. Would adding in carbs from potatoes/sweet potatoes be good, too? or is rice really just the KING and better to stick with rice?<br/>
<br/>
One last quick question, since you mentioned low thyroid, which may not actually be low thyroid... I have very low body temps lately in general. For example, last night 96.8F.. right now just texted at 97.1F... and I FEEL cold. TSH was 4.23 last tested. When I go on thyroid (tyromix 2:1 t4/t3 ratio) this gets fixed and I shoot up to 98's+ with ease. Are you saying this may not be actual low-thyroid but something else I could resolve without meds, potentially/likely?</t>

 

[Helen]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<t>Guys lets discuss this and keep making this protocol better. and I will be changing parts of it. So people can follow it.</t>

 

[Helen]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="JonnyCraig" post_id="5837" time="1512418622" user_id="71"><s>

</s>
Thanks gbolduev!<br/>
<br/>
Quick question about the diet portion... good carbs=rice - what kind of rice specifically? I like to only get and eat the best of the best, money not an option. Are we talking simply white rice here, or???<br/>
<br/>
Also, I stopped eating any carbs from wheat and whatnot. Would adding in carbs from potatoes/sweet potatoes be good, too? or is rice really just the KING and better to stick with rice?
<e>

</e></QUOTE>

Potatos are ok. I want <MENTION><s>[mention]</s>mattyb<e>[/mention]</e></MENTION> to join and add something to this plan from this diet. Potatos are ok, anything that is in Breuss protocol is ok</r>

 

[mattyb]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<t>I will jump into the convo tomorrow. Unfortunately I am tied up for the rest of today. Looking forward to a good discussion.</t>

 

[JDD]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="gbolduev" post_id="5824" time="1512415687" user_id="90"><s>

</s>
All these conditions can be caused by loss of the stomach acid due to loss of electrolytes
<e>

</e></QUOTE>

How does someone get themselves into this state initially?</r>

 

[JonnyCraig]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="gbolduev" post_id="5839" time="1512418735" user_id="90"><s>

</s>
<QUOTE author="JonnyCraig" post_id="5837" time="1512418622" user_id="71"><s>

</s>
Thanks gbolduev!<br/>
<br/>
Quick question about the diet portion... good carbs=rice - what kind of rice specifically? I like to only get and eat the best of the best, money not an option. Are we talking simply white rice here, or???<br/>
<br/>
Also, I stopped eating any carbs from wheat and whatnot. Would adding in carbs from potatoes/sweet potatoes be good, too? or is rice really just the KING and better to stick with rice?
<e>

</e></QUOTE>

Potatos are ok. I want @mattyb to join and add something to this plan from this diet. Potatos are ok, anything that is in Breuss protocol is ok
<e>

</e></QUOTE>

Thanks, I edited my post and added a question about thyroid as well.<br/>
<br/>
BTW, could we start the rough general required dosages approx of each supplement? i.e 500mg/1g,etc... will make it easier for people to follow and jump on. Just a thought.</r>

 

[Helen]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="mattyb" post_id="5840" time="1512419002" user_id="95"><s>

</s>
I will jump into the convo tomorrow. Unfortunately I am tied up for the rest of today. Looking forward to a good discussion.
<e>

</e></QUOTE>

Cool, man, I wrote some messages to you on your diet thread. I think it is a good idea we collaborate and start creating protocols for different disorders/ instead of RPF style (posting worthless studies for disorders without understanding the biochemistry.)</r>

 

[Helen]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="JDD" post_id="5842" time="1512419107" user_id="88"><s>

</s>
<QUOTE author="gbolduev" post_id="5824" time="1512415687" user_id="90"><s>

</s>
All these conditions can be caused by loss of the stomach acid due to loss of electrolytes
<e>

</e></QUOTE>

How does someone get themselves into this state initially?
<e>

</e></QUOTE>

you take steroids. You get stressed too much. You use antacid, you drink a lot of milk. You sit at the computer with blue light on non stop. just some examples. Mostly computers these days.<br/>
You get vaccines. you drink toxic water. You breath in polluted air.</r>

 

[freeflow]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="gbolduev" post_id="5845" time="1512419319" user_id="90"><s>

</s>
<QUOTE author="JDD" post_id="5842" time="1512419107" user_id="88"><s>

</s>
<QUOTE author="gbolduev" post_id="5824" time="1512415687" user_id="90"><s>

</s>
All these conditions can be caused by loss of the stomach acid due to loss of electrolytes
<e>

</e></QUOTE>

How does someone get themselves into this state initially?
<e>

</e></QUOTE>

you take steroids. You get stressed too much. You use antacid, you drink a lot of milk. You sit at the computer with blue light on non stop. just some examples. Mostly computers these days.
<e>

</e></QUOTE>

I had terrible vomiting when i was taking fin. It happened when i took maca to increase my libido which got lowered by fin. Then i stopped fin. I stopped masturbation too for a week and i was getting libido back then i crashed with an orgasm. Now 2.5 years later i tried maca again( in november) and i was vomiting again from it.</r>

 

[Jaxx]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<t>I am a bit surprised to see one protocol (theory) for both hairloss and pssd. If anything, pssd stopped my hairloss.</t>

 

[Helen]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="freeflow" post_id="5846" time="1512419524" user_id="74"><s>

</s>
<QUOTE author="gbolduev" post_id="5845" time="1512419319" user_id="90"><s>

</s>
<QUOTE author="JDD" post_id="5842" time="1512419107" user_id="88"><s>

</s>
<br/>
<br/>
How does someone get themselves into this state initially?
<e>

</e></QUOTE>

you take steroids. You get stressed too much. You use antacid, you drink a lot of milk. You sit at the computer with blue light on non stop. just some examples. Mostly computers these days.
<e>

</e></QUOTE>

I had terrible vomiting when i was taking fin. It happened when i took maca to increase my libido which got lowered by fin. Then i stopped fin. I stopped masturbation too for a week and i was getting libido back then i crashed with an orgasm. Now 2.5 years later i tried maca again( in november) and i was vomiting again from it.
<e>

</e></QUOTE>

<br/>
When you vomit you lose electrolites. and it puts you into even more sever alkalosis. Follow this protocol bud</r>

 

[barbaar]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<t>Would this still be the way to go even if you don't have any apparent digestive issues?</t>

 

[Helen]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="barbaar" post_id="5849" time="1512419960" user_id="149"><s>

</s>
Would this still be the way to go even if you don't have any apparent digestive issues?
<e>

</e></QUOTE>

Not having IBS does not mean you digest things</r>

 

[Helen]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="gbolduev" post_id="5824" time="1512415687" user_id="90"><s>

</s>
THIS IS EXPERIMENTAL PROTOCOL for those who want to try this idea. It has not been tested , it is just a theory.<br/>
<br/>
<br/>
All these conditions can be caused by loss of the stomach acid due to loss of electrolytes. Because of this you don't digest protein correctly and also your systemic protein is very low. You have lactic acidosis, with problems with hemoglobin, insulin etc.<br/>
The limiting amino acid in all this is HISTIDINE. Hemoglobin is made with it( so anemias from lead , mercury toxicities are caused by lack of histidine and not some imaginary enzyme inhibition by lead. Detox reaction from chelation are caused by the fall of this amino acid.<br/>
Cortisol is raised in all these conditions since body is missing zinc finger and mostly histidine in it. Cysteine can actually be high , since histidine is missing and not able to convert it further to glutathione and taurine pathway. Cortisol is high , but not sensitive, in most cases it causes hypokalemia, which mimics low thyroid effect. IT HAS NOTHING TO DO with your thyroid. You are not hypo thyroid, and never take any hormones. Thyroid is totally fine, when you upregulate your zinc finger, cortisol will work and will activate all copper enzymes and cortisol will increases protein synthesis and the actual level of cortisol will fall. Insensitive cortisol causes lack of protein and connective tissue, NOT THE OPPOSITE. CORTISOL ACTIVATES PROTEIN SYNTHESIS and puts ZINC IN THE CELL TO DO SO.<br/>
This is why when you are fasting your protein synthesis is even better and the body is creating new tissue at better speed and of a better quality.<br/>
<br/>
What you need to take is : <br/>
<br/>
1) First you have to increase your catalytic triad. Which is HISTIDINE , SERINE, ASPARTIC ACID( limiting in LH rise so should increase your steroids.). these you take in increased quantities( take them with a little HCL, or buy them in HCL form) . These are the center of your digestive system and your detox system. Serine and histidine are needed to start up your detox pathway, and when you are very toxic, body is using these amino acids for a detox and your digestion goes to way down, your other systemic proteins like insulin , hemoglobin go way down, they all require histidine. Your nervous system requires histidine to send signals from brain to your other organs. <br/>
<br/>
<br/>
then you need to buy amino acids: <br/>
<br/>
lysine, arginine, tyrosine, phenylalanine, alanine, glycine, valine.( these will make your digestive enzymes) You could try to substitute these with Wobenzym. <br/>
<br/>
At the same time you need to buy a product with electrolytes, If you have low sodium in blood, then look for a product that has sodium chloride, potassium chloride, magnesium chloride. <br/>
<br/>
If you have high sodium in blood, then try to take magnesium and potassium chlorides.<br/>
<br/>
Example would be <URL url="https://www.iherb.com/pr/Eidon-Mineral-Supplements-Ionic-Minerals-Electrolytes-Liquid-Concentrate-2-oz-60-ml/48759"><LINK_TEXT text="https://www.iherb.com/pr/Eidon-Mineral- ... 0-ml/48759">https://www.iherb.com/pr/Eidon-Mineral-Supplements-Ionic-Minerals-Electrolytes-Liquid-Concentrate-2-oz-60-ml/48759</LINK_TEXT></URL><br/>
<br/>
Then you take a balanced mineral supplement prefferably of organic origin. Such as pine pollen powder( not tincture) and bee pollen<br/>
<br/>
All of this you rotate. And sometimes don't take anything<br/>
<br/>
<br/>
<br/>
<br/>
Diet <br/>
<br/>
30% carbs, 50 protein, 20 fat. Vary this by increasing carbs with physical activity<br/>
<br/>
Good carbs= rice<br/>
<br/>
Good protein= sea food in form of shrimp, oysters, non fat fish<br/>
<br/>
Plenty of vegetables( like Kale, spinach, etc). Put accent on kale and spinach and try to eat it with every meal<br/>
<br/>
Some fruit, not much. Apples , nectarines, all kinds of fruits that you like.<br/>
<br/>
Milk wise, I recommend almond milk for calcium.<br/>
<br/>
Once a year, 20 day fast Breuss style.<br/>
<br/>
We can discuss this and add more things if needed to this protocol
<e>

</e></QUOTE></r>

 

[barbaar]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="gbolduev" post_id="5850" time="1512420001" user_id="90"><s>

</s>
<QUOTE author="barbaar" post_id="5849" time="1512419960" user_id="149"><s>

</s>
Would this still be the way to go even if you don't have any apparent digestive issues?
<e>

</e></QUOTE>

Not having IBS does not mean you digest things
<e>

</e></QUOTE>

Fair enough. I'm looking forward to trying this out!</r>

 

[Helen]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<r><QUOTE author="gbolduev" post_id="5824" time="1512415687" user_id="90"><s>

</s>
THIS IS EXPERIMENTAL PROTOCOL for those who want to try this idea. It has not been tested , it is just a theory.<br/>
<br/>
<br/>
All these conditions can be caused by loss of the stomach acid due to loss of electrolytes. Because of this you don't digest protein correctly and also your systemic protein is very low. You have lactic acidosis, with problems with hemoglobin, insulin etc.<br/>
The limiting amino acid in all this is HISTIDINE. Hemoglobin is made with it( so anemias from lead , mercury toxicities are caused by lack of histidine and not some imaginary enzyme inhibition by lead. Detox reaction from chelation are caused by the fall of this amino acid.<br/>
Cortisol is raised in all these conditions since body is missing zinc finger and mostly histidine in it. Cysteine can actually be high , since histidine is missing and not able to convert it further to glutathione and taurine pathway. Cortisol is high , but not sensitive, in most cases it causes hypokalemia, which mimics low thyroid effect. IT HAS NOTHING TO DO with your thyroid. You are not hypo thyroid, and never take any hormones. Thyroid is totally fine, when you upregulate your zinc finger, cortisol will work and will activate all copper enzymes and cortisol will increases protein synthesis and the actual level of cortisol will fall. Insensitive cortisol causes lack of protein and connective tissue, NOT THE OPPOSITE. CORTISOL ACTIVATES PROTEIN SYNTHESIS and puts ZINC IN THE CELL TO DO SO.<br/>
This is why when you are fasting your protein synthesis is even better and the body is creating new tissue at better speed and of a better quality.<br/>
<br/>
What you need to take is : <br/>
<br/>
1) First you have to increase your catalytic triad. Which is HISTIDINE , SERINE, ASPARTIC ACID( limiting in LH rise so should increase your steroids.). these you take in increased quantities( take them with a little HCL, or buy them in HCL form) . These are the center of your digestive system and your detox system. Serine and histidine are needed to start up your detox pathway, and when you are very toxic, body is using these amino acids for a detox and your digestion goes to way down, your other systemic proteins like insulin , hemoglobin go way down, they all require histidine. Your nervous system requires histidine to send signals from brain to your other organs. <br/>
<br/>
<br/>
then you need to buy amino acids: <br/>
<br/>
lysine, arginine, tyrosine, phenylalanine, alanine, glycine, valine.( these will make your digestive enzymes) You could try to substitute these with Wobenzym. <br/>
<br/>
At the same time you need to buy a product with electrolytes, If you have low sodium in blood, then look for a product that has sodium chloride, potassium chloride, magnesium chloride. <br/>
<br/>
If you have high sodium in blood, then try to take magnesium and potassium chlorides.<br/>
<br/>
Example would be <URL url="https://www.iherb.com/pr/Eidon-Mineral-Supplements-Ionic-Minerals-Electrolytes-Liquid-Concentrate-2-oz-60-ml/48759"><LINK_TEXT text="https://www.iherb.com/pr/Eidon-Mineral- ... 0-ml/48759">https://www.iherb.com/pr/Eidon-Mineral-Supplements-Ionic-Minerals-Electrolytes-Liquid-Concentrate-2-oz-60-ml/48759</LINK_TEXT></URL><br/>
<br/>
Then you take a balanced mineral supplement prefferably of organic origin. Such as pine pollen powder( not tincture) and bee pollen<br/>
<br/>
Also add medium dosages of vitamin B1, B2, B3 just to make sure you are getting these<br/>
<br/>
All of this you rotate. And sometimes don't take anything<br/>
<br/>
<br/>
<br/>
<br/>
Diet <br/>
<br/>
30% carbs, 50 protein, 20 fat. Vary this by increasing carbs with physical activity<br/>
<br/>
Good carbs= rice<br/>
<br/>
Good protein= sea food in form of shrimp, oysters, non fat fish<br/>
<br/>
Plenty of vegetables( like Kale, spinach, etc) PUT HEAVY ACCENT ON SPINACH AND KALE and try to eat it with every meal.<br/>
<br/>
Some fruit, not much. Apples , nectarines, all kinds of fruits that you like.<br/>
<br/>
Milk wise, I recommend almond milk for calcium.<br/>
<br/>
Once a year, 20 day fast Breuss style.<br/>
<br/>
We can discuss this and add more things if needed to this protocol
<e>

</e></QUOTE></r>

 

[Sam90]

Re: HACKSTASIS FULL protocol for CFS, HAIRLOSS, PFS, PSSD

<t>Hello there, I haven't posted on this forum before but I have been keeping up to speed. I'm a longtime pssd sufferer.<br/>
<br/>
I just looked up an electrolite test online and see that the NHS provide these. Would this test essentially determine which route we should follow? Should we all be getting this done?</t>