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Maybe the guys with low hormones have Fatty liver because the study suggests that NAFL is linked with hypogonadism

Anyone heard or used the herb Danshen? It is supposed to modulate the glucocorticoid and mineralocorticoid receptors while also raising Estrogen, could be of use

5[alpha]-reductase is a regulator of glucocorticoid action and metabolic phenotype in human liver | SFEBES2014 @Helen according to this 5ar inactivates cortisol, so any 5ar inhibitors would increase cortisol and then coupled up with a stressful event while on fin for eg would downregulate GR...

@Ingeno i had the same with Ella, I think ru works in a similar way just much more potent leading to longer term benefits

A lot of the guys on this forum with major improvements have tried ru486 beforehand anyone else notice this ?

Think this is a promising route with 5ar inhibition causing HPA Axis dysfunction Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary-adrenal axis response to restraint s... - PubMed - NCBI

Thanks for the reply, seems that you are on the right track

@bruschi11 what brand probiotics are you using ?

@Helen do you know much about the alpha 2 adrenoreceptor I know minoxidil is an agonist of this receptor

Not sure where to post this maybe it can be moved somewhere more appropriate. But is useful info on dht and 5ar 46 ways to increase DHT (2018 update) @Boris

I think with fin it causes AR overexpression throughout the body, but in my case using minox just in the brain. I know it sounds stupid but would pure dht applied to the neck etc using a Carrier eventually downregulate AR in the brain ?

Yeah this makes sense to me, considering I used minoxidil which was shown to downregulate 5ar. I also have libido on withdrawal not on alcohol

Alcohol is a positive modulator of gaba, same as Allopregnanolone. The people who feel better after drinking has low 5ar in the brain imo, which means low Allo. My strongest libido by far after drinking is when I drink vodka with red bull. Caffeine increases 5ar I read somewhere so maybe this is...

Post minox I am, it is so odd that everything feels normal when dreaming. I think norepinephrine is lower in a dream state which could make sense

Has anyone had sexual dreams where you can feel your libido, but then wake up and libido is gone?

Binge drinking alters Hdac expression. May be the reason for improvement when hungover Histone Deacetylase Gene Expression Following Binge Alcohol Consumption in Rats and Humans. - PubMed - NCBI

I’ve been doing a glass of urine for a few days every morning first thing. I’m not going to say too much but it deffo lowers brain inflammation. My skin is clearing and my eyesights getting better, good signs so far

Has anyone tried pure gum turpentine as a parasite cleanse ?

A lot of the hair tests I’ve seen are showing elevated arsenic, including mine. Sorry for spamming your log. Inhibition of Androgen Receptor Transcriptional Activity as a Novel Mechanism of Action of Arsenic

This is interesting... http://www.jneurosci.org/content/jneuro/26/5/1448.full.pdf