Recent content by D4n

  1. D4n

    Testosterone decreases brain 5AR1 and lowers allopregnenolone.

    Maybe the guys with low hormones have Fatty liver because the study suggests that NAFL is linked with hypogonadism
  2. D4n

    RANDOM QUESTIONS

    Anyone heard or used the herb Danshen? It is supposed to modulate the glucocorticoid and mineralocorticoid receptors while also raising Estrogen, could be of use
  3. D4n

    Testosterone decreases brain 5AR1 and lowers allopregnenolone.

    5[alpha]-reductase is a regulator of glucocorticoid action and metabolic phenotype in human liver | SFEBES2014 @Helen according to this 5ar inactivates cortisol, so any 5ar inhibitors would increase cortisol and then coupled up with a stressful event while on fin for eg would downregulate GR...
  4. D4n

    Why we no longer discuss Ella / RU?

    @Ingeno i had the same with Ella, I think ru works in a similar way just much more potent leading to longer term benefits
  5. D4n

    Why we no longer discuss Ella / RU?

    A lot of the guys on this forum with major improvements have tried ru486 beforehand anyone else notice this ?
  6. D4n

    Testosterone decreases brain 5AR1 and lowers allopregnenolone.

    Think this is a promising route with 5ar inhibition causing HPA Axis dysfunction Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary-adrenal axis response to restraint s... - PubMed - NCBI
  7. D4n

    TRIBULUS is antibacterial and antifungal

    Thanks for the reply, seems that you are on the right track
  8. D4n

    TRIBULUS is antibacterial and antifungal

    @bruschi11 what brand probiotics are you using ?
  9. D4n

    Another Theory for PFS ( Andregenic receptor )

    @Helen do you know much about the alpha 2 adrenoreceptor I know minoxidil is an agonist of this receptor
  10. D4n

    RANDOM QUESTIONS

    Not sure where to post this maybe it can be moved somewhere more appropriate. But is useful info on dht and 5ar 46 ways to increase DHT (2018 update) @Boris
  11. D4n

    HIGH and LOW DHT and PFS cases ( protocols , explanations, theories)

    I think with fin it causes AR overexpression throughout the body, but in my case using minox just in the brain. I know it sounds stupid but would pure dht applied to the neck etc using a Carrier eventually downregulate AR in the brain ?
  12. D4n

    HIGH and LOW DHT and PFS cases ( protocols , explanations, theories)

    Yeah this makes sense to me, considering I used minoxidil which was shown to downregulate 5ar. I also have libido on withdrawal not on alcohol
  13. D4n

    HIGH and LOW DHT and PFS cases ( protocols , explanations, theories)

    Alcohol is a positive modulator of gaba, same as Allopregnanolone. The people who feel better after drinking has low 5ar in the brain imo, which means low Allo. My strongest libido by far after drinking is when I drink vodka with red bull. Caffeine increases 5ar I read somewhere so maybe this is...
  14. D4n

    RANDOM QUESTIONS

    Post minox I am, it is so odd that everything feels normal when dreaming. I think norepinephrine is lower in a dream state which could make sense
  15. D4n

    RANDOM QUESTIONS

    Has anyone had sexual dreams where you can feel your libido, but then wake up and libido is gone?