Brainstorming & Ideas (PFS - Gbol)

[TubZy]

I don't believe he did that, I guess he is not that "stupid/crazy"..
So, when will he report back to us with something new?
.. I am also curious why he has a lab where he can test?
I mean he told us he is working in finance, why is he so specialised in bio-chemistry?...My curiosity.
Plus, even pharmaceuticals take years before to test a medicine and understand all the mechanism going on with it and testing it on rats, plus to do it, you need a big amount of money.. so this claim sounds really weird to me...
Sorry to be sceptical, but even Melcangi had a proper study and didn't find a solution.
But who knows.. he gave good explanation since now, so let's hope!!!

He answered all your questions before back on the RPF thread already....he is rich and has been testing things in the lab for a long time now, he didn't just start b/c of PFS

That's fine, thanks to clirify.
I am just an hopeless person talking, don't pay attention to me sometime ))

 

[wuf]

I can imagine he took fin again to induce PFS, he is very confident in the cure.
I especially like that his blood and hair tests are like mine when he had PFS. And he is spot on describing POIS crashes are identical to my situation.

If he really did it, he is crazy.
Hope he can cure himself and not get stucked as we are, otherwise he will join us trying to find a cure as we are doing.

 

[barbaar]

[mention]wuf[/mention] have some faith! I'm sure he wouldn't do it if he wasn't sure he could cure it.

 

[mattyb]

gbold right now.

LOOOOOOL

This is too good

 

[Jaxx]

I wonder if taking it again would result in pfs.. anyway lets hope he joins the forum again fast because most of us (incl myself) seem to be a weird mix of a child before christmas morning and tom hanks on a deserted island.

 

[Helen]

Hey guys,

Took Fin for 2 days in a row. Huge dosages. now off almost 3 days. HUGE freaking crash. Holy shit. I am testing this still. But Holy molly , I forgot how this garbage crashes people. I had panic attacks all day today. This garbage needs to be stopped.

I will report all my findings by the weekend . Did you guys have this kind of crash when you stopped Fin? I dont remember crashing this bad before

 

[wuf]

Hey guys,

Took Fin for 2 days in a row. Huge dosages. now off almost 3 days. HUGE freaking crash. Holy shit. I am testing this still. But Holy molly , I forgot how this garbage crashes people. I had panic attacks all day today. This garbage needs to be stopped.

I will report all my findings by the weekend . Did you guys have this kind of crash when you stopped Fin? I dont remember crashing this bad before

Chrashing= strong panik attacs, super anxious, brain fog, super strong headache, difficult to focus and feeling very weak... plus the sexual problems...

 

[Helen]

I cant believe they still sell this garbage . Fuck you Merck. I barely can write this right now. I am in total freaking subworld

 

[wuf]

I cant believe they still sell this garbage . Fuck you Merck. I barely can write this right now. I am in total freaking subworld

I know man, I am in the same situation so dont panick..!!

 

[Jaxx]

I never had anything like that, is this typical for pfs, but not to pssd?

 

[blindsided]

If this is really true- trying to induce PFS by taking huge doses of Fin.... All I can say is wow.

 

[Shadow]

I never had anything like that, is this typical for pfs, but not to pssd?

Dude, if you go to SA forum you will see that the same shit is the main complaint when you crash after stopping SSRIs, I had this for like a month! Its aweful! Because of similarities like this I think that the problems are the neurosteroids for pssd too!

[mention]gbolduev[/mention] sice you took huge dosages, this must be the effect:

Drug support of CNS allopregnanolone production however may have a price.
Abrupt discontinuation of antidepressants can produce withdrawal symptoms that
include anxiety, panic, and aggression. Speculatively, a cut in allopregnanolone
levels due to cessation of antidepressant use may alter GABAA composition as with
puberty and contribute to the changes in mood. Maintenance of allopregnanolone
levels through withdrawal therefore may alleviate the side effects.

This quote is from an awesome book that I found about Neurosteroids and the Nervous System(if you guys want I can upload it), this section is about SSRIs, but since Fin lower a lot Allo too, high dosages could lower it too much in too little time, so a crash can happen too.

EDIT: I uploaded the book http://www.mediafire.com/file/q925jb220kri322/neurosteroids.zip
Section 8.2 explains this. This book have so much info!!

 

[wuf]

I never had anything like that, is this typical for pfs, but not to pssd?

Dude, if you go to SA forum you will see that the same shit is the main complaint when you crash after stopping SSRIs, I had this for like a month! Its aweful! Because of similarities like this I think that the problems are the neurosteroids for pssd too!

@gbolduev sice you took huge dosages, this must be the effect:

Drug support of CNS allopregnanolone production however may have a price.
Abrupt discontinuation of antidepressants can produce withdrawal symptoms that
include anxiety, panic, and aggression. Speculatively, a cut in allopregnanolone
levels due to cessation of antidepressant use may alter GABAA composition as with
puberty and contribute to the changes in mood. Maintenance of allopregnanolone
levels through withdrawal therefore may alleviate the side effects.

This quote is from an awesome book that I found about Neurosteroids and the Nervous System(if you guys want I can upload it), this section is about SSRIs, but since Fin lower a lot Allo too, high dosages could lower it too much in too little time, so a crash can happen too.

That's for sure man.. almost everyone got this crash just wquitting Finasteride.. I am astonished about gbold, I can't believe he induced PFS just for us...
I mean, why taking that shit again, it's full of suffers which would be open to get tested and even travel to Cyprus where gbold is based, I am astonished.
I am shocked.. I will pray tonight.

 

[Helen]

In any case. I tested most of it, so I guess I can post here. Fin acts a progestin as we assumed correctly. Now the crash from fin and not ability to snap back is because there is a conflict between progesterone and cortisol created by fin. Basically after you get off fin, you have high progesterone and high cortisol and lowered 5 alpha reductase 2. Cortisol gets metabolized by 5 alpha reductase 2 , progesterone also. So you get stuck with high progesterone and high cortisol after fin. It should never be the case. Since progesterone should go high , cortisol low, cortisol high progesterone low. Since they regulate potassium in the cell.


In any case. when you take FIN it does indirectly inhibit 5 alpha reductase 2 by acting on progesterone and cortisol receptors.

After you quit fin. You have high progesterone and high cortisol. And low acitivity of 5 alpha reductase 2. The reason why it does not snap back, since progesterone keeps retaining potassium and potassium stays high in the cell. Cortisol is keeping retaining sodium and causing alkalosis which puts potassium even higher in the cell and this puts a huge pressure on cortisol.

5 alpha reductase 2 is what lowers cortisol. And it cant snap back, since cortisol is needed greatly at the moment.

So the body is stuck. It cant increase 5 alpha reductase 2. And thus cortisol goes to cortisone excessively. This lowers insulin secretion to very low since cortisone lowers insulin in the body. And you are diabetic.

So this is the my case. I am a case with low insulin. Fin has made be diabetic.

Zinc is lost in the urine like crazy now. and iron stays in the liver. Since body thinks I have tons of progesterone and tons of cortisol. DHEA grows since zinc is going away.


So now I will break this loop by tanking potassium in the cell. tanking sodium in the cell. And forcing cortisol up by blocking
cortisol to cortisone converison, which will increase my insulin back to normal. Without insulin back to normal, All my attempts to increase zinc will be met with castration since zinc will increases progesterone which will retain more potassium which will increase metabolism and puts more pressure on cortisol which will lower 5 alpha reductase even lower. since 5 alpha reductase metabolizes cortisol.

In this case , I will make my body have low potassium in the cell, and create increased cortisol( since I will stop cortisone conversion). Since increased cortisol should never exist with low cell potassium, body will have no other way to proceed but to upregulate 5 alpha reductase 2 to fight fatty liver and convert excessive cortisol . And I will get fixed from all these effects. Basically I will lower potassium, block cortisone , and force body to upregulate 5 alpha reductase 2

I will start trying to get rid of it on the weekend.

Preliminary , I think I will try acetazolamide plus licorice root as a first route to do this.

 

[wuf]

In any case. I tested most of it, so I guess I can post here. Fin acts a progestin as we assumed correctly. Now the crash from fin and not ability to snap back is because there is a conflict between progesterone and cortisol created by fin. Basically after you get off fin, you have high progesterone and high cortisol and lowered 5 alpha reductase 2. Cortisol gets metabolized by 5 alpha reductase 2 , progesterone also. So you get stuck with high progesterone and high cortisol after fin. It should never be the case. Since progesterone should go high , cortisol low, cortisol high progesterone low. Since they regulate potassium in the cell.


In any case. when you take FIN it does indirectly inhibit 5 alpha reductase 2 by acting on progesterone and cortisol receptors.

After you quit fin. You have high progesterone and high cortisol. And low acitivity of 5 alpha reductase 2. The reason why it does not snap back, since progesterone keeps retaining potassium and potassium stays high in the cell. Cortisol is keeping retaining sodium and causing alkalosis which puts potassium even higher in the cell and this puts a huge pressure on cortisol.

5 alpha reductase 2 is what lowers cortisol. And it cant snap back, since cortisol is needed greatly at the moment.

So the body is stuck. It cant increase 5 alpha reductase 2. And thus cortisol goes to cortisone excessively. This lowers insulin secretion to very low since cortisone lowers insulin in the body. And you are diabetic.

So this is the my case. I am a case with low insulin. Fin has made be diabetic.

Zinc is lost in the urine like crazy now. and iron stays in the liver. Since body thinks I have tons of progesterone and tons of cortisol. DHEA grows since zinc is going away.


So now I will break this loop by tanking potassium in the cell. tanking sodium in the cell. And forcing cortisol up by blocking
cortisol to cortisone converison, which will increase my insulin back to normal. Without insulin back to normal, All my attempts to increase zinc will be met with castration since zinc will increases progesterone which will retain more potassium which will increase metabolism and puts more pressure on cortisol which will lower 5 alpha reductase even lower. since 5 alpha reductase metabolizes cortisol.

In this case , I will make my body have low potassium in the cell, and create increased cortisol( since I will stop cortisone conversion). Since increased cortisol should never exist with low cell potassium, body will have no other way to proceed but to upregulate 5 alpha reductase 2 to fight fatty liver and convert excessive cortisol . And I will get fixed from all these effects. Basically I will lower potassium, block cortisone , and force body to upregulate 5 alpha reductase 2

I will start trying to get rid of it on the weekend.

I guess you tested yourself and this is your reaction to Finasteride but it's not a 100%common way to react to it..
In my example, minerals seems to be fine but I still have sides.

 

[Shadow]

@[mention]gbolduev[/mention] do you think that the same crap can happen with SSRIs but through 3a-HSD(the other enzime who metabolize cortisol)??

 

[Helen]

@@gbolduev do you think that the same crap can happen with SSRIs but through 3a-HSD(the other enzime who metabolize cortisol)??

I will test SSRIs, after I am done with this garbage drug. I think 3a hsd is a possibility here.

 

[Helen]

In any case. I tested most of it, so I guess I can post here. Fin acts a progestin as we assumed correctly. Now the crash from fin and not ability to snap back is because there is a conflict between progesterone and cortisol created by fin. Basically after you get off fin, you have high progesterone and high cortisol and lowered 5 alpha reductase 2. Cortisol gets metabolized by 5 alpha reductase 2 , progesterone also. So you get stuck with high progesterone and high cortisol after fin. It should never be the case. Since progesterone should go high , cortisol low, cortisol high progesterone low. Since they regulate potassium in the cell.


In any case. when you take FIN it does indirectly inhibit 5 alpha reductase 2 by acting on progesterone and cortisol receptors.

After you quit fin. You have high progesterone and high cortisol. And low acitivity of 5 alpha reductase 2. The reason why it does not snap back, since progesterone keeps retaining potassium and potassium stays high in the cell. Cortisol is keeping retaining sodium and causing alkalosis which puts potassium even higher in the cell and this puts a huge pressure on cortisol.

5 alpha reductase 2 is what lowers cortisol. And it cant snap back, since cortisol is needed greatly at the moment.

So the body is stuck. It cant increase 5 alpha reductase 2. And thus cortisol goes to cortisone excessively. This lowers insulin secretion to very low since cortisone lowers insulin in the body. And you are diabetic.

So this is the my case. I am a case with low insulin. Fin has made be diabetic.

Zinc is lost in the urine like crazy now. and iron stays in the liver. Since body thinks I have tons of progesterone and tons of cortisol. DHEA grows since zinc is going away.


So now I will break this loop by tanking potassium in the cell. tanking sodium in the cell. And forcing cortisol up by blocking
cortisol to cortisone converison, which will increase my insulin back to normal. Without insulin back to normal, All my attempts to increase zinc will be met with castration since zinc will increases progesterone which will retain more potassium which will increase metabolism and puts more pressure on cortisol which will lower 5 alpha reductase even lower. since 5 alpha reductase metabolizes cortisol.

In this case , I will make my body have low potassium in the cell, and create increased cortisol( since I will stop cortisone conversion). Since increased cortisol should never exist with low cell potassium, body will have no other way to proceed but to upregulate 5 alpha reductase 2 to fight fatty liver and convert excessive cortisol . And I will get fixed from all these effects. Basically I will lower potassium, block cortisone , and force body to upregulate 5 alpha reductase 2

I will start trying to get rid of it on the weekend.

I guess you tested yourself and this is your reaction to Finasteride but it's not a 100%common way to react to it..
In my example, minerals seems to be fine but I still have sides.

This is the mechanism of what it does. your minerals were not fine. I tested the process not the state

 

[TubZy]

In any case. I tested most of it, so I guess I can post here. Fin acts a progestin as we assumed correctly. Now the crash from fin and not ability to snap back is because there is a conflict between progesterone and cortisol created by fin. Basically after you get off fin, you have high progesterone and high cortisol and lowered 5 alpha reductase 2. Cortisol gets metabolized by 5 alpha reductase 2 , progesterone also. So you get stuck with high progesterone and high cortisol after fin. It should never be the case. Since progesterone should go high , cortisol low, cortisol high progesterone low. Since they regulate potassium in the cell.


In any case. when you take FIN it does indirectly inhibit 5 alpha reductase 2 by acting on progesterone and cortisol receptors.

After you quit fin. You have high progesterone and high cortisol. And low acitivity of 5 alpha reductase 2. The reason why it does not snap back, since progesterone keeps retaining potassium and potassium stays high in the cell. Cortisol is keeping retaining sodium and causing alkalosis which puts potassium even higher in the cell and this puts a huge pressure on cortisol.

5 alpha reductase 2 is what lowers cortisol. And it cant snap back, since cortisol is needed greatly at the moment.

So the body is stuck. It cant increase 5 alpha reductase 2. And thus cortisol goes to cortisone excessively. This lowers insulin secretion to very low since cortisone lowers insulin in the body. And you are diabetic.

So this is the my case. I am a case with low insulin. Fin has made be diabetic.

Zinc is lost in the urine like crazy now. and iron stays in the liver. Since body thinks I have tons of progesterone and tons of cortisol. DHEA grows since zinc is going away.


So now I will break this loop by tanking potassium in the cell. tanking sodium in the cell. And forcing cortisol up by blocking
cortisol to cortisone converison, which will increase my insulin back to normal. Without insulin back to normal, All my attempts to increase zinc will be met with castration since zinc will increases progesterone which will retain more potassium which will increase metabolism and puts more pressure on cortisol which will lower 5 alpha reductase even lower. since 5 alpha reductase metabolizes cortisol.

In this case , I will make my body have low potassium in the cell, and create increased cortisol( since I will stop cortisone conversion). Since increased cortisol should never exist with low cell potassium, body will have no other way to proceed but to upregulate 5 alpha reductase 2 to fight fatty liver and convert excessive cortisol . And I will get fixed from all these effects. Basically I will lower potassium, block cortisone , and force body to upregulate 5 alpha reductase 2

I will start trying to get rid of it on the weekend.

Preliminary , I think I will try acetazolamide plus licorice root as a first route to do this.

Based on the last few sentences of your post, doesn't RU do that as well? It lowers potassium, blocks cortisol etc.

And also what about Ella?

 

[Helen]

In any case. I tested most of it, so I guess I can post here. Fin acts a progestin as we assumed correctly. Now the crash from fin and not ability to snap back is because there is a conflict between progesterone and cortisol created by fin. Basically after you get off fin, you have high progesterone and high cortisol and lowered 5 alpha reductase 2. Cortisol gets metabolized by 5 alpha reductase 2 , progesterone also. So you get stuck with high progesterone and high cortisol after fin. It should never be the case. Since progesterone should go high , cortisol low, cortisol high progesterone low. Since they regulate potassium in the cell.


In any case. when you take FIN it does indirectly inhibit 5 alpha reductase 2 by acting on progesterone and cortisol receptors.

After you quit fin. You have high progesterone and high cortisol. And low acitivity of 5 alpha reductase 2. The reason why it does not snap back, since progesterone keeps retaining potassium and potassium stays high in the cell. Cortisol is keeping retaining sodium and causing alkalosis which puts potassium even higher in the cell and this puts a huge pressure on cortisol.

5 alpha reductase 2 is what lowers cortisol. And it cant snap back, since cortisol is needed greatly at the moment.

So the body is stuck. It cant increase 5 alpha reductase 2. And thus cortisol goes to cortisone excessively. This lowers insulin secretion to very low since cortisone lowers insulin in the body. And you are diabetic.

So this is the my case. I am a case with low insulin. Fin has made be diabetic.

Zinc is lost in the urine like crazy now. and iron stays in the liver. Since body thinks I have tons of progesterone and tons of cortisol. DHEA grows since zinc is going away.


So now I will break this loop by tanking potassium in the cell. tanking sodium in the cell. And forcing cortisol up by blocking
cortisol to cortisone converison, which will increase my insulin back to normal. Without insulin back to normal, All my attempts to increase zinc will be met with castration since zinc will increases progesterone which will retain more potassium which will increase metabolism and puts more pressure on cortisol which will lower 5 alpha reductase even lower. since 5 alpha reductase metabolizes cortisol.

In this case , I will make my body have low potassium in the cell, and create increased cortisol( since I will stop cortisone conversion). Since increased cortisol should never exist with low cell potassium, body will have no other way to proceed but to upregulate 5 alpha reductase 2 to fight fatty liver and convert excessive cortisol . And I will get fixed from all these effects. Basically I will lower potassium, block cortisone , and force body to upregulate 5 alpha reductase 2

I will start trying to get rid of it on the weekend.

Preliminary , I think I will try acetazolamide plus licorice root as a first route to do this.

Based on the last few sentences of your post, doesn't RU do that as well? It lowers potassium, blocks cortisol etc.

And also what about Ella?

Yes, I will test those also. I just want to test better the activity of 5 alpha reductase 2 after RU cortisol blockage. I assume it will go down. May be that is why people who used RU short term did good, and the slow snap back will take a month.

I want to force the snap back. I aint got a month to be in this garbage state

I know exactly what it did to me, and I want to hit it there. I want to block cortisol to cortisone conversion. And I want to make the body want less cortisol. body needs less cortisol in slow metabolism. It does not need cortisol since metabolism is low. So it will try to upregulate 5 alpha reductase to get rid of cortisol. Cortisol is lowerd by 5 alpha reductase 2 and cortisone pathway. 1) I block cortison pathway, and 2) lower metabolism. It will scream uncle and increase 5 alpha reductase 2.

This is what is happening in hairloss. increased insulin and cortisol and low metabolism. increases 5 alpha reductases 2 .
You become horny as hell but you are getting fatty liver from 5 alpha reductase 2