Creatine and DHT

[Jamie]

Are there people who workout and tried supplementing creatine? I took it one year ago and it really impoved strength. Now I found study claiming creatine increases DHT levels by ~50%.
http://journals.lww.com/cjsportsmed/Abstract/2009/09000/Three_Weeks_of_Creatine_Monohydrate.9.aspx

It is weird but there are no other studies about that while cratine supplements are massively produced and easy to buy.
And there are my concerns, may short term creatine cycling(3-4weeks e.g.) contribute to some serious long-term imbalances in the body? Doesn't it chelate or antagonize any vital minerals?

 

[Jaxx]

I used some while coming off ssri, still makes me wonder if that did anything

 

[mattyb]

I took creatine for a while probably 5-6 years ago, got much stronger with it, but also got some symptoms of low estrogen like really bad and irregular joint pain that I had never gotten before. It stopped as soon as I stopped taking it.

 

[opiath]

I took creatine for a while probably 5-6 years ago, got much stronger with it, but also got some symptoms of low estrogen like really bad and irregular joint pain that I had never gotten before. It stopped as soon as I stopped taking it.

I have high estrogen and the same thing happens to me when I take creatine.
Really really bad joint pain.
I read somewhere that creatine synthesis uses up to 70% of the methyl groups in the methylation cycle.
Maybe if methylation is upregulated and you take creatine, the methyl groups have to be used somewhere else like COMT and this brings down estrogen.

 

[JonnyCraig]

I've been using creatine on and off for almost 20 years now.

It's the shit. Plain and simple. So many positive things to say about it both to increase physical output but also mental capacity.

I do not use it anymore due to fear of it increasing hairloss.

TUBZY - Let's hear your thoughts?

 

[JonnyCraig]

Taken from SV:

"Despite being statistically relevant the absolute changes in the DHT levels van der Merwe et al. observed in the study at hand were neither physiologically relevant (DHT remained well within the reference range), nor totally inexplicable. Being afraid of hair loss, let alone prostate cancer, in response to the consumption of (untainted) creatine supplements is thus totally unwarranted.

And just in case you still want to freak out, I suggest you keep sitting on your ass for the rest of your life and refrain from ever playing football or any other sport again... why? Well according to Lupo et al., your DHT levels will double during a single football match. This and similar observations by Hawkins in a middle aged men on a 12-months aerobic exercise program (14.5% increase with moderate intensity cardio 6x per week; cf. Hawkins. 2008), as well as the results from Aizawa et al. who were able to demonstrate "that acute exercise enhances the local bioactive androgen metabolism in the skeletal muscle of both sexes" and not just men, do as bro-logic dictates suggest that any kind of physical activity will make you hair fall out and your prostate grow... now tell me how realistic is that?"

Full article: http://suppversity.blogspot.ca/2013/10/creatine-dht-hair-loss-prostate-cancer.html

 

[Jamie]

Taken from SV:

"Despite being statistically relevant the absolute changes in the DHT levels van der Merwe et al. observed in the study at hand were neither physiologically relevant (DHT remained well within the reference range), nor totally inexplicable. Being afraid of hair loss, let alone prostate cancer, in response to the consumption of (untainted) creatine supplements is thus totally unwarranted.

And just in case you still want to freak out, I suggest you keep sitting on your ass for the rest of your life and refrain from ever playing football or any other sport again... why? Well according to Lupo et al., your DHT levels will double during a single football match. This and similar observations by Hawkins in a middle aged men on a 12-months aerobic exercise program (14.5% increase with moderate intensity cardio 6x per week; cf. Hawkins. 2008), as well as the results from Aizawa et al. who were able to demonstrate "that acute exercise enhances the local bioactive androgen metabolism in the skeletal muscle of both sexes" and not just men, do as bro-logic dictates suggest that any kind of physical activity will make you hair fall out and your prostate grow... now tell me how realistic is that?"

Full article: http://suppversity.blogspot.ca/2013/10/creatine-dht-hair-loss-prostate-cancer.html

Single sport match last ~90 min. But that article make quite sense. Results of that research could be shown in a light that they looks concerning. Wish there be more tests on that

 

[Jamie]

So with that sligtly elevated DHT level the reason could be e. g. exercising. Those who took creatine were a bit stronger than before and could workout harder.

I am actually trying to find out what made so many imbalancies in my body and I found that:

Now, let's go to the really bad guy here, beta-alanine. To be concise: beta-alanine blocks renal conservation of taurine and causeshypertaurinuria - loss of taurine in the urine. This, in tuurn, causes urinary loss of magnesium, which worsens sulfotransferase activity as well as lots ofother necessary enzymatic processes. If you give carnosine, you lose taurine and magnesium. There are lots of references, but you can start with Dr.Charles Scriver's work referenced above, because all of this biochemistry (carnosine, beta-alanine, taurine, etc.) is closely related." ~ [mention]Nighteyes[/mention]

Could taking beta-alanine as a pre workout and having lots of mental stress cause magnesium depletion(-51%)?

 

[Area-1255]

I've always noticed immediate mild 'stimulating' effects on Creatine. Like a mild Proviron. So yes I think it raises DHT.