Hairloss - Thoughts on S-equol / soy isoflavones ?

Aleksandr

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Seems they both reduce DHT by reducing free testosterone (but not total testosterone) which could be great for hairloss.
They also increase estrogen... one possible reason why those on hormonal replacement therapy for a sex change (men to women) regrow hair: both reducing DHT and increasing estrogen

Where as decreasing DHT (i.e. finasteride) is only one side of the problem, so while effective for stopping hairloss it doesnt promote new growth

Read this article: To fight hair loss we can reduce DHT by lowering free testosterone. But be careful.
 
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Aleksandr

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C'mon guys! Nothing?!

I actually have a male friend who has high SHBG who has a great head of hair and is 32, looks like juvenile hair line.
Also my ex partner had high SHBG and she had a super thick super long maine.
 

Trump_1776

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C'mon guys! Nothing?!

I actually have a male friend who has high SHBG who has a great head of hair and is 32, looks like juvenile hair line.
Also my ex partner had high SHBG and she had a super thick super long maine.
Hey bruv, hair is not worth reducing free testosterone.
We need more men this day and age, not more cucks!
 

tallglass13

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I really don't think we should even be focusing on DHT. DHT is a male hormone that is very necessary to our manhood. Finasteride is a synthetic Progesterone, and Progesterone increases the metabolic rate by putting Potassium in the cell. That is probably why it grows hair. Fin taking down DHT is a side effect, because Progesterone opposes testosterone in high doses. Young healthy men have strong progesterone levels, almost as much as female in the luteal phase.
 

Trump_1776

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I really don't think we should even be focusing on DHT. DHT is a male hormone that is very necessary to our manhood. Finasteride is a synthetic Progesterone, and Progesterone increases the metabolic rate by putting Potassium in the cell. That is probably why it grows hair. Fin taking down DHT is a side effect, because Progesterone opposes testosterone in high doses. Young healthy men have strong progesterone levels, almost as much as female in the luteal phase.
Are we sure it comes down to the metabolic rate though?
 

tallglass13

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Are we sure it comes down to the metabolic rate though?
no, and I think the same as you. My personal belief still, is tightness of the galea do to stress. Ray Peat says balding men show high Prolactin and Cortisol. Which don't "cause" hair loss on their own, but when there is stress, muscles tighten in the neck, shoulders, and perimeter of the skull.
I have been using a scalp strap now for 2 months. My scalp is much more pliable. I don't think I will see hair regrowth for another few months if this theory is correct.
 

RebelWithACause

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I think hair loss in some guys could be from metabolic syndrome.

The wrong diet and the wrong way of eating for a long time.

When I got fatter that is also when I got more hairloss in that period for example. I was eating really crappy food. When I ate McDonalds my scalp would itch like insanity all over. Plus a lot of shedding after. Since that time I always knew there was a correlation between diet and hairloss. Since then I started to clean up my diet and lower my BF% and this also lowered my hair loss.

My friend who has aggressive hair loss has a very bad diet and masturbates a lot, has sex a lot and he has love handles and a soft appearance in the body. Would not be surprised if he has problems with insulin.

Androgenetic alopecia, metabolic syndrome, and insulin resistance: Is there any association? A case–control study

There were statistically significant differences regarding mean values of body weight (P < 0.001), height (P = 0.002), waist circumference (P < 0.001), body mass index (P < 0.001), systolic (P < 0.001), and diastolic blood pressure (P < 0.001), fasting glucose (P < 0.001), triglycerides (P < 0.001), high-density lipoprotein cholesterol (P < 0.01), fasting insulin (P = 0.02) and homeostasis model assessment of insulin resistance (P < 0.001) between cases and controls. A statistically significant association was found between AGA and MS (P = 0.002) and between AGA and IR (P < 0.001). Multiple logistic regression analysis revealed that waist circumference (>102 cm) was the most significant risk factor for developing MS. It increased the risk of MS by 1.25-folds (95% CI = 1.10-1.42, P < 0.001).

Insulin resistance increases oxidative stress, free radicals and inflammation. This could also put too much pressure on glutathione??

Update metabolic Syndrome and Hairloss
 
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RebelWithACause

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I think there is too many possibilities. Too complicated for me. But I do believe there is a correlation between how you eat, your lifestyle and your habits.
 

tallglass13

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However, Progesterone/finasteride does grow some hair. And woman are mostly protected from balding do to their higher progesterone. All men have DHT, but not all men go bald on top. So DHT has mostly good effects for men. Prgesterone and DHT has to be in balance, but there is something to bald guys having tight shiny heads. that must be addressed.
 

tallglass13

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Haidut's says its metabolic as well. higher NAD/NADH ratio. is what is needed. Progesterone supports metabolic rate, so improving NAD. Finasteride is a mutant progesterone. So there is a case for higher NAD+ ratio.
 

Aleksandr

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Hey bruv, hair is not worth reducing free testosterone.
We need more men this day and age, not more cucks!
It doesnt reduce total testosterone though, isnt that the used form? I didnt think free T mattered?
I admit I am a novice on hormones though
 

Aleksandr

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Agreed. The key would be to find healthy, androgenic men with full heads of hair, and probably also beards and see what their configuration - hormones, mineral composition, etc. - is like. But I don't think there's anything of that sort to be found. Black Americans have worse hairlines, but they don't bald as much as White Americans and one reason could be that they have more estrogen. Asians often have full heads of hair, but they're very effeminate. Thailand has the least amount of balding males in the world I think, but they simultaneously have the highest amount of transgenders. In Europe, baldness is very common. My oversimplified theory just judging from observing the people with different configurations is this:

  • balding people who don't look like pussies. They usually look significantly older than they are, especially at the time their balding starts. Good example: Michael Stevens from VSauce. I think their problem is mostly too high DHT.
  • balding people who look like pussies: They usually look about the age they are, but they look weak in most cases. I think they have low progesterone and either low or medium androgens, medium to high estrogen, and probably high prolactin in most cases.
  • non-balding people who look rather effeminate: High progesterone and they tend to look younger than they are. Low to medium androgens.
  • non-balding people who don't look like pussies: Balanced. Maybe not balanced in a holistic sense, but all the ratios are okay enough to not trigger hair loss and okay enough for them to be 'normal' men.
This guy is quite hairy; he has a thick full dark beard and thick fall dark head hair. He did a TEI too and he was a fast oxi with higher mg than ca, higher na than mg and higher k than na.
 

Aleksandr

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no, and I think the same as you. My personal belief still, is tightness of the galea do to stress. Ray Peat says balding men show high Prolactin and Cortisol. Which don't "cause" hair loss on their own, but when there is stress, muscles tighten in the neck, shoulders, and perimeter of the skull.
I have been using a scalp strap now for 2 months. My scalp is much more pliable. I don't think I will see hair regrowth for another few months if this theory is correct.
What about people who have sex changes and regrow their hair?

My current believed theory is that sex change drugs reduce DHT and increase estrogen. Estrogen is pro growth so grows the hair back, while dht is only what causes it to fall out

So maybe those with high dht and no balding have high estrogen too

Or maybe they just have high total T, high shbg (thus low free t and low dht) but still look manly??
 

Aleksandr

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1,285
I think hair loss in some guys could be from metabolic syndrome.

The wrong diet and the wrong way of eating for a long time.

When I got fatter that is also when I got more hairloss in that period for example. I was eating really crappy food. When I ate McDonalds my scalp would itch like insanity all over. Plus a lot of shedding after. Since that time I always knew there was a correlation between diet and hairloss. Since then I started to clean up my diet and lower my BF% and this also lowered my hair loss.

My friend who has aggressive hair loss has a very bad diet and masturbates a lot, has sex a lot and he has love handles and a soft appearance in the body. Would not be surprised if he has problems with insulin.

Androgenetic alopecia, metabolic syndrome, and insulin resistance: Is there any association? A case–control study

There were statistically significant differences regarding mean values of body weight (P < 0.001), height (P = 0.002), waist circumference (P < 0.001), body mass index (P < 0.001), systolic (P < 0.001), and diastolic blood pressure (P < 0.001), fasting glucose (P < 0.001), triglycerides (P < 0.001), high-density lipoprotein cholesterol (P < 0.01), fasting insulin (P = 0.02) and homeostasis model assessment of insulin resistance (P < 0.001) between cases and controls. A statistically significant association was found between AGA and MS (P = 0.002) and between AGA and IR (P < 0.001). Multiple logistic regression analysis revealed that waist circumference (>102 cm) was the most significant risk factor for developing MS. It increased the risk of MS by 1.25-folds (95% CI = 1.10-1.42, P < 0.001).

Insulin resistance increases oxidative stress, free radicals and inflammation. This could also put too much pressure on glutathione??

Update metabolic Syndrome and Hairloss
I think inflammation itself has a direct link to hairloss
 

Trump_1776

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403
It doesnt reduce total testosterone though, isnt that the used form? I didnt think free T mattered?
I admit I am a novice on hormones though
I don't know, was responding to the claim in the first post.
I don't have the answers. I just have PFS
 

RebelWithACause

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From what I read online:

No free testosterone is your bioavailable testosterone. Lower that and you will have symptoms of "low testosterone".

SHBG binds to testosterone and renders it inactive. So if you have high SHBG you have less free testosterone floating around.

Total testosterone does not say that much. You can have 1000 ng/dl but if it is all binded by SHBG you will still feel like you have low testosterone.

It needs to be balanced. I do think low SHBG is correlated with diabetes 2:

Low Sex Hormone-Binding Globulin Levels Associate with Prediabetes in Chinese Men Independent of Total Testosterone

The association between sex hormone-binding globulin and type 2 diabetes in Nigerian men

Maybe low SHBG is a lack of SHBG (for whatever reason) and this causes too many androgens floating around for what your body can handle. Then you get hair loss. Which could be a reason why people w/ metabolic syndrome (diabetes, hypertension, etc) get hair loss.

I think young people often have higher SHBG. I also read guys who had low SHBG on a TRT forums and they had low libido and all types of problems. It is not that clear cut.
 

Aleksandr

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Aleksandr

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Green Tea and hair loss

Green tea / green tea extract also raises shbg. This website suggest in combination use with soy isoflavones

It says low shbg can mean hairloss and acne @Orion have u ever tested your hormones? What were your results?
Btw I read elsewhere: vitamin E also raises shbg , so the liver flush could help acne / hairloss here too.

Other things that raise shbg:
Moderate exercise
Lower sugar
Higher fibre
Soy
Vitamin e
 

Orion

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It says low shbg can mean hairloss and acne @Orion have u ever tested your hormones? What were your results?

I did test SHBG years ago, when looking into thyroid and adrenals, in range of course, and doctors are 'you are fine'.
 

RebelWithACause

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2,613
Green Tea and hair loss

Green tea / green tea extract also raises shbg. This website suggest in combination use with soy isoflavones

It says low shbg can mean hairloss and acne @Orion have u ever tested your hormones? What were your results?
Btw I read elsewhere: vitamin E also raises shbg , so the liver flush could help acne / hairloss here too.

Other things that raise shbg:
Moderate exercise
Lower sugar
Higher fibre
Soy
Vitamin e

Seriously soy is absolute trash food. I would never eat it unless you have something like PFS where it can help to cycle it. Same for other estrogenic plants. I don't think they are that great for you.

Eating some fermented soybeans (natto) won't kill you but all this soy drinking and eating is nonsense. Soy is a junkfood full with anti-nutrients and phytic acid. Plus the feminising effect it has on men.

Men are acting like faggots in this day and age already and I think it is from the nutrition. And soy is in a lot of stuff now. Even in meats from Subway for example. It will become more and more. Soy will be in all crap because it's cheap as fuck.

What I think:

Anti-hairloss is not becoming more female with anti-DHT, anti-testosterone, anti-whatever. Unless you want to live unoptimally. You will be a weak bitch with hair. Hooray. You will die from the wind blowing in your face.

Anti-hairloss is going back to a natural lifestyle. Be in the sun, some exercise and manual labor (use the body), swimming in the ocean, short fasting (or long if you need to heal), natural foods that you can find in nature - not "soy milk". I would say animal foods are very important for every body. The amount and what type you need to figure out yourself.

Less sex. Kill all your addictions. Clean everything up not just the body. But the lifestyle as well.

People are abusing their bodies all the time. Every day. In a natural enviroment you would have a lot more rest. Now people are stressed every day from social media, their stupid relationships and other BS. Plus they also want to have sex every day. They also want to eat junkfood every day. They want to use drugs, drink caffeine, drink alcohol. People are willingly killing themselves by pushing the body through this. Forcefully.

If they can't do it anymore they will take something that will keep them going for example caffeine, anabolic steroids, supplements, etc.

Think for one moment. It is because of the society that has been created.

Which is an artificial layer on top of the natural laws of nature. A natural human would live in nature, woods, by the sea, they would be active, etc. This is why all those things are HEALTHY - now people have to make time for doing those things lol.

No natural human would have sex all the time. There was simply no time for this. Or masturbation behind a screen HAHA. WTF!

I bet you most humans did not have hairloss in nature. Maybe in older age because the body becomes less capable of adapting. But now we have guys in their teens going bald.

I think it is a good idea to adapt some of the things our ancestors did naturally. And incorporate it in your life. And try to live more like them.