JonnyCraig
Well-Known Member
- Messages
- 250
According to this: Anti-aromatase effect of resveratrol and melatonin on hormonal positive breast cancer cells co-cultured with breast adipose fibroblasts - ScienceDirect
Quite interesting.
Highlights
•
Testosterone stimulates breast tumor proliferation via aromatization to E2.
•
Melatonin and resveratrol are aromatase inhibitors in this co-culture model.
•
Resveratrol is 1000 times less potent than melatonin in aromatase inhibition.
•
Melatonin is equally potent as the therapeutic aromatase inhibitor letrozole.
•
Melatonin could be a potential novel chemopreventive agent in breast cancer therapy.
Quite interesting.
Highlights
•
Testosterone stimulates breast tumor proliferation via aromatization to E2.
•
Melatonin and resveratrol are aromatase inhibitors in this co-culture model.
•
Resveratrol is 1000 times less potent than melatonin in aromatase inhibition.
•
Melatonin is equally potent as the therapeutic aromatase inhibitor letrozole.
•
Melatonin could be a potential novel chemopreventive agent in breast cancer therapy.