So, the question is this....... are we saying that it is a receptor issue, regardless of high or low DHT? Yes going back on finasteride as
@PFStinks and
@Jack17 have done may just be a patch, but if it resensitized everything again, and we then properly titrated down off of Fin again, isn’t that the win? I ask only because the first time I quit Fin, that’s what I did, and everything was great. Second time, cold turkey, nightmare. If all we have to do is get back on Fin, feel better, then get off the proper way, is that what we should be aiming for? And then, once off of Fin, balance out without the receptors being overloaded. I’m sure I’m not getting this right, but.......
this is what Pfsstinks has been trying. and it did not work in his case.
that was my idea is that if someone goes back on fin and then slowly comes off. then the body will have time to downregulate protein levels of the receptor.
meaning make it less sensitive.
when you come off cold turkey, then the receptor is super sensitive and that is why it gets shut down , since in places where DHT is, it is super sensitive,
and the brain shuts down ARs , DHT works and works fine,
what does not work is testosterone. since it is the same ARs which got shut down.
so in DHT sensitive tissues, when you took FIN, the ARs became super sensitive.
and in testostorone sensitive tissues, ARs are normal. since you never were down on testosterone on fin.
so when DHT goes up, body senses too much DHT action, and puts on a lock on AR to lower its action, this is beyond the receptor.
so this basically lowers DHT action to normal. but lowers testosterone action to below normal. since ARs were not overexpressed in cells with testosterone.
This is how Cdnuts got cured, he cycled R andro, and slowly downregulated DHT receptors, and testosterone started to work.
But I think people have 2 problems here, one with DHT and one with gaba.
This is why different hormone levels.