PSSD - Thyroid connection?

J

Jaxx

Well-Known Member
Messages
683
Although mentioned briefly in other topics, i'd like to highlight the thyroid connection to PSSD, possibly PFS.
Since i have PSSD i have elevated TSH, but not low T3/T4, so no experience with thyroid hormones. Others have mentioned high TSH as well.
I also experienec a gentle, constant pressure on my throat continuously (thyroid?).

Interestingly, ive read logs where people experienced windows or are even cured, where they say the relief came from the thyroid and then spread further.

Anyone know of any obvious link to the thyroid and maybe experience with thyroid hormones so-far?
 
tanedout

tanedout

Well-Known Member
Messages
538
Jaxx post_id=5347 time=1511908015 user_id=61 said:
Although mentioned briefly in other topics, i'd like to highlight the thyroid connection to PSSD, possibly PFS.
Since i have PSSD i have elevated TSH, but not low T3/T4, so no experience with thyroid hormones. Others have mentioned high TSH as well.
I also experienec a gentle, constant pressure on my throat continuously (thyroid?).
Click to expand...

I'm in the same boat, high TSH, but not low T3/T4. Pressure around the base of the neck frequently. Hair analysis says low thyroid and low adrenal function.

Interestingly some stuff posted up on one of the accutane forums about a link to low thiamine (B1) causing issues for adrenal and thyroid function due to it's role in the creation of NADPH
NADPH oxidase and thyroid function
An interesting aspect of the NADPH oxidase system is that it plays a major role in thyroid function. Thyroid hormone synthesis is dependent on NADPH in both the thyroid and the liver. In the thyroid, two separate NADPH oxidase systems are used to generate free radicals, particularly hydrogen peroxide(H2O2), that are used to build the thyroid hormones T4 and T3(5, 6). In the liver, the less active T4 is converted in to T3 by an NADPH-dependent enzyme, 5'-deiodinase(7, 8) that utilizes reduced glutathione to make this conversion. Again, the solution to problems like this are much more complex than just throwing thiamine at them. T4 and T3 help regulate the conversion of riboflavin to FAD(9, 10, 11) which participates in many of the thiamine dependent enzymes as a cofactor and both FAD and selenium are needed for the glutathione cycle to work properly.
Click to expand...

http://synergyhw.blogspot.co.uk/2015/06/thiamine-gut-health-immune-system-and.html
 
J

Jaxx

Well-Known Member
Messages
683
that is interesting. I also respond quite strong to licorice root (adrenal link), ever tried that? No libido effect for me, but definately more energy.
 
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