I have been taking one packet of off brand emergen-c, experimenting with cycling for awhile now. It seems to be one of the common denominators for my symptom relief. I actually stumbled upon it serendipitously when I was sick and noticed improvements in symptoms when taking it. The three components that are 100% + of daily value is obviously Vitamin C, (1000% DV, B6, (500% DV as well as B12, (500% DV.) I have noticed an improvement in well being as well as some other enhancements. I know there are hormonal benefits to all three of these and it's probably no secret here but I wanted to share as Its one of the few things that I seemed to benefit from consistently and I also like the fact that it is an extremely low risk supplement.