the progesterone doubt

Go_faster_Sonic

Well-Known Member
Messages
173
Talking about protocols, i see that there’s a progesterone cycling protocol some guys attempt.
there’s something that does not make sense in my mind.
If it is said that progesterone is 5-alpha-rd inhibitor (type 1? type 2?)… but it is also the precursor of dhp (through 5 alpha rd), which is the precursor of allopregnanolone (through 3 alpha hsd)… does progesterone inhibits it’s own transformation in allopregnanolone? @Helen

the pathway is the following:

  • Progesterone > 5 alpha rd > Dihydroprogesterone > 3 alpha hsd > Allopregnanolone.