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Heh, yes I wouldn't be worried but I've not started the RU yet. Looks like Oestradiol's been on the decline since PFS. Eek.

Hi folks - started the log thread here. Join in at leisure, send good thoughts and let's hope we smash this or learn something. :)

Hello all, due to popular demand I'm logging this separately and splitting off from the original thread, from about this point. Long and short is, we're trying a 5-day run of RU to reset the HPA axis, and then see if that solves PFS. 800mg/day in a single PM dose. Will begin Saturday night...

No, fairly sure they're out now too. :(

You thinking 400mg R-Andro for instance, along with the 8mg Silodyx? Uuurgh just ITCHING to try this.

Wait... WUF got cured?? Oh boy that guy really deserved it, he was battling that's for sure. "Screwing chicks until he's tired". Man, those were the days... Sorry for the OT, as you were.

Thought it'd be worth just checking in. I'm dropping this one for the time being Ran it for three weeks, I'm actually on the up (mentally more than sexually, pretty much the same sexually) but I'm not sure it's been this really that's done it. Maybe another time.

Thanks Boris. I was going to wait at least 20 days, as the second guy who bounced back from dexamethasone took that long iirc. In any case, I'll let bloods stabilise etc. Call it three weeks then from last dose? Then run bloods then run RU again, likely 1.2g/day for 5 days for round 2. I'll...

Will probably depend on how it goes. If nothing changes after or I slide back to baseline then yes I'll 'complete' the study in that case. If it ends up curing me I'll keep checking in, will definitely stick around and will make a LOT of time and cash available for followup experiments as we'll...

Okay, will do. When I'm about to get started I'll make a log thread and link it here/link back to here. It'll only be 5 days + aftermath/postmortem after all, shouldn't be too long.

I thought that the other day, but I've pretty much hijacked this one now - didn't want to clutter the forum up.

You still want some of us running those two Vit D tests Helen? I might leave mine for a few weeks now until the RU run is done and out of me.

Well no real 'news' news today, just some admin. All 'pre' bloods in the post going out, should have the lot by Friday. The remaining RU is on it's way now, should be in my hand Monday. Found THIS where it's been run before, and a little bit of 'human' info to go on. Preparing for some low mood...

Argh! I'd love to be doing this but I'm all occupied. @ncsugrad fella you available for this one? I want to wait until a good month after the RU (just in case the HPA correction takes that long) before I try anything else. Anyone?

Cheers again all - I might go for all in one dose in that case. TEI results are in too btw. Pre-bloods getting taken tomorrow still, should have those by next Friday, then we begin next weekend! Remaining RU ordered too.

Maybe in the spirit of 'big sledgehammer' (which I think is the approach here, just from my impressions) I'll call it 800mg/day for 5 days. Money is no concern currently, but if $2k (eg two hefty cycles + bloods) cures PFS here then it's worth it, if I'm constantly dropping $2k on cycles it's...

Boris that is solid gold thank you hugely for finding those! Okay, so now we know people have run these doses before and not exploded or anything. Nice to be aware of the potential, mild sides too! Off the back of this then, shall I get a couple more in and run 800mg/day for 5 days? What do we...

Could be, unfortunately I'm racing the TEI results from the other week, but expect those any day. Recent bloods for a cortisol test were: Test - 20 (8.64-29) Test/Cortisol Ratio - 0.05 Cortisol - 411 (166-507) Any good?

If fatigue means sleep is better, top notch! Hehe. I'll be unhappy if it's that bad, looking forward to the gym. Do we think it'll be reasonable to use caffeine (coffee/tea) during this? I work in IT (business support, manage a couple of teams) and I've picked my battles, that week I'm free...