Re: - High Alt Correcting some Neuro and Other issues in PFS/ Drug Syndromes
1.
Walker said:I experienced the same thing during PFS. I travel a lot for work and still do, but when I would travel, always during the flight symptoms would change. Spontaneous boners, brain fog dissapate, etc. It became less noticeable the more and more I got better, but it always made me wonder what was going on - truly bizarre.Maybe some relation with hydrostatic pressure... just like climbers using Coca tea back in the day in Peru... to help fight off altitude sickness, some vague relations in the mood regulating (and also sexual function regulating) neurosteroids, that were diminished by 5arII inhibition.
-I offer no conclusions on that, but some of this is interesting, some is relevant:
-2. Studies:
[PDF] Altitude training improves glycemic control
SM Chen, HY Lin, CH Kuo - Chin J Physiol, 2013 - synergyfitness.com.au
… that most of such experiments were per- formed under ischemic or anoxic condition (oxygen
concentration close to zero), which is apparently lethal to humans and cannot comparable to
high altitude hypoxia condition … Herbert, J.
Neurosteroids, brain damage, and mental illness …
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Prolonged exposure to hypobaric hypoxia transiently reduces GABAA receptor number in mice cerebral cortex
MS Viapiano, AMM de Novara, SF de Plazas… - Brain research, 2001 - Elsevier
… Animals chronically exposed to hypobaric hypoxia, which resembles
high altitude conditions,
present alterations in the myelination of fibres from the … in the total density of receptor complexes
and increase in the response to endogenous modulators (ie
neurosteroids) with no …
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[PDF] rero.ch
Erythropoietin modulates the neural control of hypoxic ventilation
M Gassmann, J Soliz - Cellular and molecular life sciences, 2009 - Springer
… Increasing ventilation is the most important hypoxic response when mammals are acutely exposed
to
high altitude [51], but it also plays a crucial role in the acclimatization … Note, however, that these
date do not discard a putative interaction of cerebral Epo and
neurosteroids …
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The neuronal control of hypoxic ventilation
M Gassmann, MT van Patot… - Annals of the New York …, 2009 - Wiley Online Library
… is lowered, a situation occurring in patients suffering from chronic obstructive pulmonary diseases
(COPD) or in people exposed to
high altitude … Notably, steroid hormones are also synthesized
in the brain and are called
neurosteroids.8 These hormonal factors are classically …
Cited by 25 Related articles All 11 versions