Minoxidil Acts as an Antiandrogen: A Study of 5α-reductase Type 2 Gene Expression

noprop

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What is a common side? Insomnia? Shrinkage? Please, can you list a bit what he exactely had. It would be very useful for all of US, I think. Thank you!
 

hello

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Guys, it's just one thing that really bogles my mind.

How that there are a majority of people that never got PFS after minox or finasterid ? Now i am not saying that haven't gotten other sides... just not got PFS or erectile dysfunctions. So how those people are different than those that got ED ? What it's the thing that protected them ?
Thanks
 
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noprop

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There are two twins in Germany (pvdl and his brother). They got the same symptoms at the same time. So epigenetics seem to be a root. Different people had full but temporary (in some cases permanent) recover due to some protocols. I know 90% percent of them and what they took.
I posted several months ago a comprehensive protocol how to cure that BS. From analysis to the protocol.
If its epigenetics, you can change it.
 

MNK99

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Exactly, what's done/undone can be reversed somehow. takes longer and more effort than popping that demon pill (not the good kind of demon, a garbage demon pill).
 

MNK99

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I think minoxidil is shit, and a piss poor drug with limited and not beating some other topicals for hair loss.
My hair loss is probably genetic + medn caused... or something else (what that is, not sure).


I used Spironolactone cream (homemade when I realized how) - initially, from the HLT site or similar vendors.


The morning version had caffeine. WORKED well... THought I'd lose all my hair... 3.5 years or so, damn good hair (but less than pre-loss).
I had major TE from Adderall probably maintained and regrew some on Dexedrine with breaks but still had lines or breaks in hair and changed texture a bit (far improved, but my fucking hair changed which to me was odd and scary at the time). YEARS later, Lamotrigine raped my hair - hair in shoes, closet, computer, fridge, windows, everywhere.

Also, hair was different, but that wasn't Spiro cream, it was Adderall/ amphetamines..... Dexedrine was less harsh, but this stuff reduced hair shed from
Hair all over and also: eyebrows.
Possibly dex or adderall make my fast oxidation even faster. Same with nicotine, caffeine. All vasoconstrictors as well, tightening blood vessels and flow in the scalp.
There is something that was recommended to me - I forget the name, it was on some Psyche Forum.


By a guy, that I told I was really sick to, (PFS). And he said my hair loss isn't the genetic, normal kind and "Minoxidil won't work".
I know if I agree/ think the same as that guy, but he suggested some topical dermatologists use at times... Sounds something like "Cetaphil" but it isn't cetaphil (that's a face wash or a cream).

That was a psyche forum so they bad mouthed me for bad mouthing various psyche meds, methods, and the DSM, and some other things (correctly, with better English, Scientific, Logical, and Analytical Reasoning compared to them). [I know this is a run-on and or a comma-splice, this is not a graded paper. ;) ]

Anyways, the point is : That guy's med list: was like 60-80 trialled things.

So I listened to him.
I was gonna buy it but I was too sick at that point. Could try now or later, but maybe TEI will help hair anyways. Otherwise, money, fuck drugs (shit drugs at least).

SPIRO* never hurt sex drive OUTSIDE of twice a day application. I THINK*** minoxidil one or two times 4-5 yrs ago made it hard to get an erection and also caused some upper facial hair growth, possibly ear hair growth. I was already just trying adderall, and my terrible experiences in mind, I freaked the fuck out and threw it and other surrounding items. Tried it like 3.5-4.5 yrs later alongside Finasteride. Well - it didn't go well, nearly died... SO if fin's a shit drug and it works and minoxidil literally works for nearly no one, I threw that bitch away.


SPIRO cream OWNS minoxidil easily. But it's probably shitty for other reasons.
POSSIBLY began my slight testicle pain, but that could be other things as well. Sometimes pretty bad. Maybe primed me for PFS but I don't think so.
ANYTHING topical can go SYSTEMIC. RUBBING amphetamines or cocaine in various mucous membranes will go systemic as would lying in a bathtub full of ANTHRAX. Despite what clowns may say.

Someone needs to die for the hair loss alone, let alone PFS. AND effexor. Lost like 4 yrs, maybe 5 maybe 10 not sure.
That's what I think. Time? Money? They gotta go man.
"SPIRO*" = the cream.

THe pill will fuck everything up - things that people didn't think were possible.
I got my stuff from south america.

Mortar and pestle, menthol, aloe, some heavy base cream, possibly some propylene glycol, gloves, crush pills, rosemary water to help the smell, etc.
100mg a pill, need like 20 for a strong solution in a small vial/bottle. I forget, written down in an old note - spiro cream recipe. Higher than 6-7% is unlikely to be stable.
Maybe liposomal solutions like those Hasson & Wong guys (for their topical finasteride). I'd recommend against topical fin (considered it, I must have been out of my mind).
 
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MNK99

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-Look at all those actors that looked good and you can literally tell who was on finasteride and or minox.
-Puffy face, sagging eyes, better hair? Fatter, fatter face, dumber, etc. You can literally tell...
-Fue from top 10 surgeon in a 3-10 million popn city? you cannot tell.
-MINOX is shit @hello.
-I mean a great surgeon, not some mickey mouse douchebag (obviously). Not some detroit medical school washout nor a Dr. W. Rassman.
-MY DAD grew up in a small village... and the same drugs exist from when he was in his 20's. Just lol at hair loss drugs. Another pharma miracle. SMD pharma.

-There's probably studies showing horseradish or wasabi or alcoholism outperform minoxidil. It's a jackoff of a drug. SAFER than fin it seems, but for amazing hair growth, I'd rather do a rain dance on Merck's grave, with a giant erection, and an award winning orgasm.
 
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Minime

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-Look at all those actors that looked good and you can literally tell who was on finasteride and or minox.
-Puffy face, sagging eyes, better hair? Fatter, fatter face, dumber, etc. You can literally tell...
-Fue from top 10 surgeon in a 3-10 million popn city? you cannot tell.
-MINOX is shit @hello.
-I mean a great surgeon, not some mickey mouse douchebag (obviously). Not some detroit medical school washout nor a Dr. W. Rassman.
-MY DAD grew up in a small village... and the same drugs exist from when he was in his 20's. Just lol at hair loss drugs. Another pharma miracle. SMD pharma.

-There's probably studies showing horseradish or wasabi or alcoholism outperform minoxidil. It's a jackoff of a drug. SAFER than fin it seems, but for amazing hair growth, I'd rather do a rain dance on Merck's grave, with a giant erection, and an award winning orgasm.
It is interesting to me that many posts recently have mentioned fatter faces. This is the opposite of what I thought pfs did to people. One of my strongest symptoms is muscle wasting and thus my face is skinny and narrow with no fat. This happened immediately on my first crash. Skinnier wrists, arms, everything on me simply got smaller. It is the reason I created my user name of “Mini-Me”...because I am merely a miniature replica of the man I once was. I thought most if not all pfs sufferers had muscle wasting, bone loss and tissue loss resulting in a very skinny appearance. But I guess that is not the case as numerous others have mentioned fatty faces. I just find it interesting that once again the symptoms of pfs are not necessarily the same and can actually be the opposite from person to person.
 

MNK99

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I didn''t really gain any facial fat. I lost like 10lb in a week... and then gained like 30. GOOD again, very strong - 95 dips yesterday but need to take it easy. 50 today.
No more workouts for a time for me. BC, I cannot just lift light, I need to force myself not to go. BUt* I am bored and trying to kill various bad habits, and gym is there... but I'll walk or swim or play soccer.

I did have facial fat loss (and was lean before this relatively). Leaner now. BUT for a time, looked like hard work in a controlled diet and exercise regime was ruined... but thankfully, I was wrong. I am hopeful some facial changes will reverse. Mostly cannot tell unless I forcefully exaggeratedly smile.

Jaw and such still there, I do have some neck under jaw chin fat/skin but I did lose like 70-80lb at 16-18 years of age. 250-180lb. 192lb right now AND stronger than ever lifting wise. I have been a better runner, but I don't run all that much these days. (i run around the house and when late enough... and sweat a lot in lifts and keep it under one min rest or one min or so if I feel I'm going too fast).

I meant more minoxidil does that to a lot of people's faces. MOST minox sides can probably go if PFS goes too. But realself has crazy case reports of Minox.
They probably wouldn't dare diss Finasteride.
 
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TubZy

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Aflac94

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It is interesting to me that many posts recently have mentioned fatter faces. This is the opposite of what I thought pfs did to people. One of my strongest symptoms is muscle wasting and thus my face is skinny and narrow with no fat. This happened immediately on my first crash. Skinnier wrists, arms, everything on me simply got smaller. It is the reason I created my user name of “Mini-Me”...because I am merely a miniature replica of the man I once was. I thought most if not all pfs sufferers had muscle wasting, bone loss and tissue loss resulting in a very skinny appearance. But I guess that is not the case as numerous others have mentioned fatty faces. I just find it interesting that once again the symptoms of pfs are not necessarily the same and can actually be the opposite from person to person.

I have pfs symptoms similar to you. Who knows if we ever nail down what the hell happened , but the fact that the symptoms are so variable gives more weight to Helen’s theories rather than some androgen receptor issue. But then again who knows
 

pedal

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Any experience with caffeine topical solutions ?
I wanted to try it years ago but couldn't find the website, I think it was a German company and it was a lotion sold in a toothpaste tube.
 

noprop

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499
I have pfs symptoms similar to you. Who knows if we ever nail down what the hell happened , but the fact that the symptoms are so variable gives more weight to Helen’s theories rather than some androgen receptor issue. But then again who knows
Consider that overall there are AR! If they are shut down, the body is obviously in imbalance and tries forex by shutting down reducing 5ar and testo to resentisize the receptors. Even in the liver (and gut) hormons and their precursors and important peptids are build. It is a systemic thing, but people are waiting for the one pill solution.
 

Aflac94

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Consider that overall there are AR! If they are shut down, the body is obviously in imbalance and tries forex by shutting down reducing 5ar and testo to resentisize the receptors. Even in the liver (and gut) hormons and their precursors and important peptids are build. It is a systemic thing, but people are waiting for the one pill solution.

I hope one day we find out
 

PAS

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110
Yeah it was mentioned in the hair threads here
I can't find the thread by seaching for caffeine. Do you remember the title?

Do you think this caffeine solution is safe? I can't find articles linking 5 AR2 to caffeine, but thats because that angle hasn't been researched. If somebody has done this method can they share their experience. I would like to hop onto this ASAP but it may work the same way as minox, decreasing 5ar2. What do you guys think
 

pedal

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I would like to hop onto this ASAP but it may work the same way as minox, decreasing 5ar2. What do you guys think
On German tv I saw an ad for caffeine based hair paste. But when I started losing my hair I couldn't find it anymore on the internet in English. I wondered why that was and why I couldn't find anything bad about finasteride. Maybe the company went bankrupt or men sued it when it didn't work? In USA you can get every type of snake oil you can imagine for male pattern baldness but until recently it wasn't easy to find caffeine based shampoo or topical lotion. Maybe that means it works and it's safe? You'd think it would be a no brainer since there is some logic to the science compared to selling men Emu oil and other eccentric items to trigger regrow.

From what I read caffeine is a DHT inhibitor on the scalp while it promotes DHT if you drink coffee. And the best way to regrow bald spots is to use onion juice for at least 6 weeks.

In my opinion it's safe to try, of course it's better if you don't have pfs and brainfog but it won't do something sorghum shampoo can't reverse. I think it's a minor tweak where you're stimulating hair follicles with a natural food you were deficient in, not where you're breaking one part of your body to get results in another. That's why taking most supplements is stupid, there is no free lunch, you cause problems for slight improvement in one area.
 
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PAS

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Thanks @pedal. How sure are you about the onion juice? Have you seen any actual instances where it worked?