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It's easy to see how things turn into a vicious circle too. Impaired bile acid metabolism -> inability to absorb fat soluble vitamins and other nutrients -> SIBO etc takes hold (lack of bile to control bad bacteria) -> bile acid synthesis further impaired as you can't absorb nutrients like...

If so, do you have the following defect? rs10503019 18 55454377 AA You can search your raw data for this, ie the text file you download from 23andme. It's a defect which results in problems metabolising bile acids. 109 ATP8B1 rs10503019 15.06 A 100...

Wouldn't be surprised if the root cause of our issues was down to one of these Bile Acid Synthesis Disorders - NORD (National Organization for Rare Disorders)

Choline requirements apparently depend on genetics, and estrogen which seems a bit surprising? Choline Metabolism Provides Novel Insights into Non-alcoholic Fatty Liver Disease and its Progression

I get this from taking TUDCA - everything goes super dry, and my hair feels like straw and starts coming out really easily. I found taking SAM-e alongside it stops that however - my hair then goes really soft despite the same dose of TUDCA. Recently I've tried taking MSM instead of the SAM-e to...

Things I've found that help are tribulus (make some tea with the contents of the capsule), but this depends on how you respond to it, some people don't seem to get on with it Ginger tea (shop bought, also has licorice in) also seems very effective, and fennel tea is supposed to be good too...

Yeah it's not that common. eBay or Amazon are the best places. For UDCA I managed to get a prescription, but like i said it's definitely not as effective, so would be 2nd choice

In my experience if I stop eating gluten/grains like bread, pastry etc then the white tongue is gone within 3-4 days. If I re-start eating bread for example, then it comes back quickly. Currently the only grains I eat is white rice which seems to cause no issues with white tongue

TUDCA is basically just UDCA with a taurine molecule attached. I personally find TUDCA is better, but both are good! For me they reduce/eliminate pain in the liver area and make me sweat again, I think just basically improve liver function! Grape seed extract also has benefits for the liver...

https://waset.org/publications/9999944/grape-seed-extract-in-prevention-and-treatment-of-liver-toxic-cirrhosis-in-rats Interesting study which found benefits in using GSE alongside UDCA to prevent and manage liver cirrhosis. UDCA/TUDCA and GSE are two sups I respond well to, although haven't...

I would see a doctor or go to ER. They can do some blood tests and give proper advice. If TEI includes a lot betaine hydrochloride then maybe it's been too acidic for your stomach, but I'm just speculating - best to go discuss with a doctor.

What do you reckon helped you out with that situation? My food intolerances are much worse than they used to be - can't cope with fat at all now!

Anyone else currently trying this protocol out of interest?

Berberine is supposed to be a powerful anti-fungal, and also biofilm disruptor. Only saw recently that Area1255 recovered taking berberine (and horny goat weed) for 6 months, but the anti-fungal activities could be a factor there. Obviously there is the guy who recovered taking antibiotics...

You could always try a supplement like 'daosin' to reduce histamine (I think hay fever is basically when histamine is released in response to the pollen being a trigger), or try supplementing things that increase production of the dao enzyme

You still get it with PFS?! Since getting PAS I never get flu/colds or even hay fever, and I used to get it pretty badly

You've definitely got the right sort of potassium! I was supplementing with potassium citrate for a while, but it made no impact on my bloods (potassium stayed low), but when I switched to potassium chloride it increased to the middle of the range. I find if I take more than I need however then...

@Area-1255 were you high or low DHT when you had PSSD? What is the thinking behind this combination specifically? And what effects did you notice from this combo?

@Ocguy That gut protocol you followed looks really interesting - might be worth setting up a dedicated thread to that so that it's easily searchable, and people who try it can add their experiences!

First one is here; https://hackstasis.com/threads/tanedout-hair-mineral-analysis.210/